MW: 3357.933 g/mol | 29 Amino Acids | GHRH(1-29) | Form: Lyophilized | Purity: 99%+ HPLC
Sermorelin is a 29-amino-acid synthetic analogue of GHRH(1-29) — the first 29 amino acids of endogenous growth hormone-releasing hormone — studied for pituitary GHRH-receptor binding and natural pulsatile GH secretion. A key research distinction: unlike direct GH administration, Sermorelin preserves the body’s physiological GH feedback loop, making it a tool for studying GH-axis regulation without bypassing endogenous control mechanisms. Research applications also include cardiovascular pathway studies, GABA receptor modulation, orexin/sleep-cycle research, and bone and tissue repair models. Each vial contains 5mg of lyophilized Sermorelin at 99%+ HPLC-verified purity, with a batch-specific Certificate of Analysis available for download. *
Sermorelin
GHRH(1-29) — First 29 aa of Growth Hormone-Releasing Hormone
Mechanism of Action• GHRH Receptor Binding & Physiological GH Feedback: Binds GHRH receptors on pituitary somatotrophs to stimulate pulsatile GH release while preserving the endogenous GH/IGF-1 feedback loop — a key distinction vs direct GH administration.
• Cardiovascular Pathway Research: Studied in cardiac models for reducing cardiomyocyte apoptosis, enhancing extracellular matrix production, stimulating angiogenesis, and reducing inflammation following ischemic events.
• GABA Receptor & Orexin Pathway Research: Studied for interactions with GABA receptors in neurological models, and for effects on orexin signaling in sleep-cycle and wakefulness-regulation research.
• Bone & Tissue Repair Research: Examined for effects on bone-mineral-density pathways, extracellular matrix production, and tissue-repair mechanisms in preclinical research models.
Together these make Sermorelin a key tool in GHRH-receptor, GH-axis, cardiovascular, and multi-system pathway research.
| Compound | Sermorelin (GHRH(1-29) — first 29 aa of growth hormone-releasing hormone) |
| Sequence | Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg (29 aa) |
| Amino Acids | 29 |
| Formula | C₁₄₉H₂₄₆N₄₄O₄₂S |
| MW | 3357.933 g/mol |
| CAS Number | 86168-78-7 |
| Purity | ≥ 99% by HPLC |
| Identity | Confirmed by LC-MS |
| Form | Lyophilized powder |
| Vial Size | 3mL glass vial · 5mg (in stock) · 5mg (currently OOS on Biogenesis) |
| Additives | None |
| Batch COA | Available for download |
- GHRH receptor binding & physiological GH-axis research
- GH feedback loop preservation vs direct GH administration studies
- Cardiac pathway research: cardiomyocyte, ECM, angiogenesis
- GABA receptor modulation & neuroprotection research
- Orexin signaling & sleep-cycle regulation research
- Bone-density & tissue-repair pathway research models
Storage: Store lyophilized powder at -20°C long term; protect from light and moisture.
Handling: Research use only; handle by licensed, qualified professionals with PPE.
FEATURED INGREDIENTS
All Ingredients
GHRH(1-29) — GH Feedback Preserved
Studied for signalling the pituitary to release GH naturally — and unlike direct GH administration, preserves the body’s own GH feedback loop in endocrine research.
Cardiovascular Research Models
Examined in cardiac models for heart-cell protection, extracellular matrix production, and angiogenesis pathway research following ischemic events.
GABA & Sleep-Cycle Research
Studied for GABA receptor interactions and effects on orexin signalling — relevant to neural inhibition and sleep-cycle regulation research models.
PRODUCT BENEFITS
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GHRH(1-29) — Natural Sequence Analogue First 29 amino acids of endogenous GHRH, binding the pituitary GHRH receptor to stimulate pulsatile GH release while preserving the body’s natural GH feedback loop.
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Cardiovascular Research Models Studied in cardiac models for cardiomyocyte protection, extracellular matrix production, and angiogenesis pathway research following ischemic events.
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GABA Receptor Pathway Research Studied for interactions with GABA receptors in neurological research models — pathways relevant to neural inhibition and neuroprotection studies.
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Sleep-Cycle & Orexin Research Studied for effects on orexin signaling and sleep-cycle regulation in endocrine and neurological research models.
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Bone & Tissue Repair Research Examined for effects on bone-density and tissue-repair pathways, including extracellular matrix production, in preclinical research models.
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99%+ HPLC-Verified Purity Independently verified by third-party labs via HPLC and LC-MS; batch-specific COA and SDS available pre-purchase.
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Sermorelin is the natural GHRH(1-29) sequence — studied for triggering pulsatile GH release the way the body naturally does, without bypassing the feedback system. Beyond the GH axis, it is studied in cardiovascular models for heart-cell and vascular pathway research, in GABA pathway models for neural inhibition research, and in orexin/sleep-cycle models — making it a multi-system endocrine research tool.*
WHAT TO EXPECT
Independently verified by third-party labs
Batch number printed on every vial
Orders before 2 PM EST ship same business day
Plain FedEx/UPS, return label: Shipping Manager
Real human responses within hours
Independently verified by third-party labs
Batch number printed on every vial
Orders before 2 PM EST ship same business day
Plain FedEx/UPS, return label: Shipping Manager
Real human responses within hours
GHRH Receptor Binding & Physiological GH Feedback
Binds GHRH receptors on pituitary somatotrophs to stimulate pulsatile GH release while preserving the endogenous GH/IGF-1 feedback loop — a key research distinction from direct GH administration, which bypasses this feedback mechanism.
Cardiovascular Pathway Research
Studied in cardiac research models for reducing cardiomyocyte apoptosis, enhancing extracellular matrix production, stimulating angiogenesis, and modulating inflammation following ischemic events.
GABA, Orexin & Bone / Tissue Research
Examined for interactions with GABA receptors in neurological pathway research, effects on orexin signalling in sleep-cycle models, and bone-density and tissue-repair pathways in preclinical models.
ALL DETAILS
- GHRH Receptor Binding & Physiological GH Feedback — Binds GHRH receptors on pituitary somatotrophs to stimulate pulsatile GH release while preserving the endogenous GH/IGF-1 feedback loop — a key research distinction from direct GH administration, which bypasses this feedback mechanism.
- Cardiovascular Pathway Research — Studied in cardiac research models for reducing cardiomyocyte apoptosis, enhancing extracellular matrix production, stimulating angiogenesis, and modulating inflammation following ischemic events.
- GABA, Orexin & Bone / Tissue Research — Examined for interactions with GABA receptors in neurological pathway research, effects on orexin signalling in sleep-cycle models, and bone-density and tissue-repair pathways in preclinical models.
The "Sermorelin" Peptide |
No fillers | No artificial additives | No excipients | 99%+ HPLC verified · batch COA | No repackaged imports | No human-use claims |
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Sermorelin Peptide
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Other Peptide |
The "Sermorelin" Peptide
| Compare to: | Sermorelin Peptide |
Other Peptide |
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| No fillers | ||
| No artificial additives | ||
| No excipients | ||
| 99%+ HPLC verified · batch COA | ||
| No repackaged imports | ||
| No human-use claims |
FAQs
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper Complex) is a naturally occurring copper-binding tripeptide studied extensively in preclinical and in vitro research models. It is primarily researched for its role in tissue repair, collagen synthesis, wound healing, gene expression modulation, hair follicle biology, and antioxidant defense pathways.
Lyophilized means the compound has been freeze-dried — water is removed under vacuum to produce a stable powder. This process significantly extends shelf life and preserves compound integrity during storage and shipping. Lyophilized peptides are the research-grade standard because they maintain purity far longer than liquid formulations.
Each batch of GHK-Cu is independently verified at ≥99% purity using HPLC (High-Performance Liquid Chromatography). Identity is further confirmed by LC-MS (Liquid Chromatography-Mass Spectrometry). A batch-specific Certificate of Analysis (COA) is available for download before purchase.
Store lyophilized GHK-Cu at −20°C upon receipt. Keep protected from light, heat, and moisture. Do not open the vial until needed for your research protocol. Under proper storage conditions, lyophilized GHK-Cu maintains compound integrity for up to 24 months.
No. Peptides Verse does not provide reconstitution, dosing, or administration guidance of any kind. All reconstitution protocols are the sole responsibility of the qualified researcher or institution receiving this compound. This product is strictly for in vitro and laboratory research use only.
Yes. A batch-specific COA is available for every vial of GHK-Cu sold by Peptides Verse. The COA includes HPLC purity data, LC-MS identity confirmation, lot number, and testing lab details. It can be downloaded directly from the product page before or after purchase.
GHK refers to the free tripeptide (Glycyl-L-Histidyl-L-Lysine) without copper. GHK-Cu is the copper-chelated form — where a Cu² ion is bound to the tripeptide. The copper-chelated form is the biologically active version studied in most published research on wound healing, collagen synthesis, and gene expression modulation.
No. GHK-Cu from Peptides Verse is strictly for in vitro research and laboratory experimentation only. It is not intended for human or animal use of any kind. By purchasing, the buyer confirms they are a qualified researcher or institution and accepts full responsibility for safe handling and use.
All orders are shipped via FedEx with temperature-appropriate packaging to protect compound integrity during transit. Packaging is discreet — plain FedEx or UPS with no product branding on the exterior. Orders placed before 2 PM EST ship same business day.
Due to the nature of research chemicals, all sales are final once a vial has been opened or the seal broken. If you receive a damaged or incorrect item, contact support@peptidesverse.com within 48 hours of delivery with your order number and photos.