MW: 5195.908 g/mol | 44 Amino Acids | N-Terminus Modified | Form: Lyophilized | Purity: 99%+ HPLC
Tesamorelin is a 44-amino-acid synthetic analogue of growth hormone-releasing hormone (GHRH), modified at the N-terminus with a trans-3-hexenoic acid group that protects it from DPP-4 enzyme degradation — extending its research half-life compared to natural GHRH. It binds GHRH receptors on the pituitary to stimulate pulsatile GH release and downstream IGF-1 production. Research applications include visceral adipose tissue metabolism, lipid pathway studies, peripheral nerve regeneration models, and cognitive/GABA pathway research. Each vial contains 10mg of lyophilized Tesamorelin at 99%+ HPLC-verified purity, with a batch-specific Certificate of Analysis available for download. *
Tesamorelin
N-terminus modified GHRH analogue
Mechanism of Action• DPP-4 Resistance via N-Terminus Modification: The trans-3-hexenoic acid group at the N-terminus protects the peptide from dipeptidyl peptidase-4 (DPP-4) degradation, extending the research half-life vs natural GHRH.
• GHRH Receptor Binding & GH/IGF-1 Axis: Binds GHRH receptors on pituitary somatotrophs to stimulate pulsatile GH secretion and downstream IGF-1 and IGFBP-3 production in laboratory models.
• Visceral Adipose & Lipid Metabolism: Through the GH/IGF-1 axis, studied for effects on visceral adipose tissue metabolism, triglyceride levels, and lipid profiles in preclinical models.
• Nerve Regeneration & Cognitive Pathways: Studied in peripheral nerve repair models and for GABA pathway effects and cognitive-function modulation in neurological research.
Together these make Tesamorelin a key tool in GHRH receptor, GH/IGF-1 axis, metabolic, and neurological research.
| Compound | Tesamorelin (N-terminus modified GHRH analogue) |
| Amino Acids | 44 + trans-3-hexenoic acid N-terminus modification |
| Sequence | Unk-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu |
| Formula | C₂₂₃H₃₇₀N₇₂O₆₉S |
| MW | 5195.908 g/mol |
| CAS Number | 901758-09-6 (document ref) · Note: 218949-48-5 also cited — verify vs COA |
| N-Terminus Mod | trans-3-hexenoic acid — DPP-4 resistance, extended half-life |
| Purity | ≥ 99% by HPLC |
| Identity | Confirmed by LC-MS |
| Form | Lyophilized powder |
| Vial Size | 3mL glass vial · 10mg (single size) |
| Additives | None |
| Batch COA | Available for download |
Tesamorelin is studied across multiple preclinical research areas:
- GHRH receptor binding & pituitary GH-axis research
- IGF-1 & IGFBP-3 axis stimulation research
- Visceral adipose tissue (VAT) metabolism research models
- Lipid & triglyceride pathway research
- Peripheral nerve regeneration & repair models
- GABA pathway & cognitive-function research models
For research teams investigating GHRH receptor pathways, GH/IGF-1 axis, and metabolic regulation.
Storage & HandlingStorage: Store lyophilized powder at -20°C long term; protect from light and moisture.
Handling: Research use only; handle by licensed, qualified professionals with PPE.
FEATURED INGREDIENTS
All Ingredients
N-Terminus Modified GHRH
A 44-aa GHRH analogue with a trans-3-hexenoic acid group at the N-terminus — shields it from DPP-4 enzyme breakdown for an extended research half-life.
Pituitary GH-Release Research
Studied for binding GHRH receptors on the pituitary to signal sustained growth hormone and IGF-1 release in endocrine research models.
Visceral Fat & Lipid Research
Researched for effects on how the body stores and metabolises visceral fat and lipid levels through the GH/IGF-1 axis.
PRODUCT BENEFITS
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N-Terminus Modified GHRH Analogue 44-aa GHRH analogue with a trans-3-hexenoic acid N-terminus modification that resists DPP4 degradation — giving it an extended half-life vs natural GHRH.
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Pituitary GH-Release Research Binds GHRH receptors on the pituitary to stimulate sustained, pulsatile GH secretion and downstream IGF-1 axis activation in endocrine research models.
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Visceral Adipose Tissue Research Studied for effects on visceral (abdominal) fat storage and metabolism in lipid and metabolic pathway research models.
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Lipid Pathway Studies Researched for effects on triglyceride levels, cholesterol fractions, and overall lipid metabolism in preclinical models.
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Nerve Regeneration Research Examined for supporting peripheral nerve repair and regeneration pathways in nerve injury models.
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99%+ HPLC-Verified Purity Independently verified by third-party labs via HPLC and LC-MS; batch-specific COA and SDS available pre-purchase.
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Tesamorelin is a GHRH analogue modified at the N-terminus to resist rapid breakdown in the body — giving it a longer active window than natural GHRH. It binds GHRH receptors on the pituitary gland to trigger pulsatile GH release and downstream IGF-1 production. Through the GH/IGF-1 axis, it is studied for effects on visceral fat metabolism, lipid pathways, peripheral nerve repair, and cognitive pathway research.*
WHAT TO EXPECT
Independently verified by third-party labs
Batch number printed on every vial
Orders before 2 PM EST ship same business day
Plain FedEx/UPS, return label: Shipping Manager
Real human responses within hours
Independently verified by third-party labs
Batch number printed on every vial
Orders before 2 PM EST ship same business day
Plain FedEx/UPS, return label: Shipping Manager
Real human responses within hours
DPP-4 Resistance via N-Terminus Modification
The trans-3-hexenoic acid group at the N-terminus shields the peptide from dipeptidyl peptidase-4 (DPP-4) degradation — the modification that gives Tesamorelin an extended research half-life compared to natural GHRH, which is rapidly broken down in circulation.
GHRH Receptor Binding & GH/IGF-1 Axis
Binds GHRH receptors on pituitary somatotrophs to stimulate pulsatile GH secretion, and downstream production of IGF-1 and IGFBP-3 — the key axis studied in GH-pathway, metabolic, and regenerative research models.
Visceral Adipose, Lipid & Nerve Research
Through the GH/IGF-1 axis, studied for effects on visceral adipose tissue metabolism, triglyceride and lipid pathways, and peripheral nerve regeneration — as well as cognitive/GABA pathway effects in neurological research models.
ALL DETAILS
- DPP-4 Resistance via N-Terminus Modification — The trans-3-hexenoic acid group at the N-terminus shields the peptide from dipeptidyl peptidase-4 (DPP-4) degradation — the modification that gives Tesamorelin an extended research half-life compared to natural GHRH, which is rapidly broken down in circulation.
- GHRH Receptor Binding & GH/IGF-1 Axis — Binds GHRH receptors on pituitary somatotrophs to stimulate pulsatile GH secretion, and downstream production of IGF-1 and IGFBP-3 — the key axis studied in GH-pathway, metabolic, and regenerative research models.
- Visceral Adipose, Lipid & Nerve Research — Through the GH/IGF-1 axis, studied for effects on visceral adipose tissue metabolism, triglyceride and lipid pathways, and peripheral nerve regeneration — as well as cognitive/GABA pathway effects in neurological research models.
The "Tesamorelin" Peptide |
No fillers | No artificial additives | No excipients | 99%+ HPLC verified · batch COA | No repackaged imports | No human-use claims |
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Tesamorelin Peptide
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Other Peptide |
The "Tesamorelin" Peptide
| Compare to: | Tesamorelin Peptide |
Other Peptide |
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| No fillers | ||
| No artificial additives | ||
| No excipients | ||
| 99%+ HPLC verified · batch COA | ||
| No repackaged imports | ||
| No human-use claims |
FAQs
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper Complex) is a naturally occurring copper-binding tripeptide studied extensively in preclinical and in vitro research models. It is primarily researched for its role in tissue repair, collagen synthesis, wound healing, gene expression modulation, hair follicle biology, and antioxidant defense pathways.
Lyophilized means the compound has been freeze-dried — water is removed under vacuum to produce a stable powder. This process significantly extends shelf life and preserves compound integrity during storage and shipping. Lyophilized peptides are the research-grade standard because they maintain purity far longer than liquid formulations.
Each batch of GHK-Cu is independently verified at ≥99% purity using HPLC (High-Performance Liquid Chromatography). Identity is further confirmed by LC-MS (Liquid Chromatography-Mass Spectrometry). A batch-specific Certificate of Analysis (COA) is available for download before purchase.
Store lyophilized GHK-Cu at −20°C upon receipt. Keep protected from light, heat, and moisture. Do not open the vial until needed for your research protocol. Under proper storage conditions, lyophilized GHK-Cu maintains compound integrity for up to 24 months.
No. Peptides Verse does not provide reconstitution, dosing, or administration guidance of any kind. All reconstitution protocols are the sole responsibility of the qualified researcher or institution receiving this compound. This product is strictly for in vitro and laboratory research use only.
Yes. A batch-specific COA is available for every vial of GHK-Cu sold by Peptides Verse. The COA includes HPLC purity data, LC-MS identity confirmation, lot number, and testing lab details. It can be downloaded directly from the product page before or after purchase.
GHK refers to the free tripeptide (Glycyl-L-Histidyl-L-Lysine) without copper. GHK-Cu is the copper-chelated form — where a Cu² ion is bound to the tripeptide. The copper-chelated form is the biologically active version studied in most published research on wound healing, collagen synthesis, and gene expression modulation.
No. GHK-Cu from Peptides Verse is strictly for in vitro research and laboratory experimentation only. It is not intended for human or animal use of any kind. By purchasing, the buyer confirms they are a qualified researcher or institution and accepts full responsibility for safe handling and use.
All orders are shipped via FedEx with temperature-appropriate packaging to protect compound integrity during transit. Packaging is discreet — plain FedEx or UPS with no product branding on the exterior. Orders placed before 2 PM EST ship same business day.
Due to the nature of research chemicals, all sales are final once a vial has been opened or the seal broken. If you receive a damaged or incorrect item, contact support@peptidesverse.com within 48 hours of delivery with your order number and photos.