{"title":"CJC-1295","description":"","products":[{"product_id":"tone-cjc-1295-without-dac-5mg-ipamorelin-5mg-gh-secretion-research","title":"Tone · CJC-1295 Without DAC (5mg) + Ipamorelin (5mg) · GH-Secretion Research","description":"\u003cp\u003e\u003cspan\u003eThis peptide blend contains \u003c\/span\u003e\u003cb\u003eCJC-1295 (5mg) and Ipamorelin (5mg)\u003c\/b\u003e\u003cspan\u003e, totaling \u003c\/span\u003e\u003cb\u003e10mg\u003c\/b\u003e\u003cspan\u003e, and is designed to \u003c\/span\u003e\u003cb\u003esynergistically enhance growth hormone (GH) secretion\u003c\/b\u003e\u003cspan\u003e through two distinct mechanisms:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\"\u003e\n\u003cb\u003eCJC-1295\u003c\/b\u003e\u003cspan\u003e activates \u003c\/span\u003e\u003cb\u003egrowth hormone-releasing hormone (GHRH) receptors\u003c\/b\u003e\u003cspan\u003e, stimulating \u003c\/span\u003e\u003cb\u003enatural pulsatile GH production\u003c\/b\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\"\u003e\n\u003cb\u003eIpamorelin\u003c\/b\u003e\u003cspan\u003e functions as a \u003c\/span\u003e\u003cb\u003eselective GH secretagogue\u003c\/b\u003e\u003cspan\u003e, mimicking \u003c\/span\u003e\u003cb\u003eghrelin\u003c\/b\u003e\u003cspan\u003e while suppressing \u003c\/span\u003e\u003cb\u003ecortisol and prolactin spikes\u003c\/b\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eTogether, these peptides contribute to:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\"\u003e\u003cb\u003eMuscle growth and enhanced recovery\u003c\/b\u003e\u003c\/li\u003e\n\u003cli aria-level=\"1\"\u003e\u003cb\u003eFat loss and metabolic optimization\u003c\/b\u003e\u003c\/li\u003e\n\u003cli aria-level=\"1\"\u003e\u003cb\u003eImproved bone density and joint healing\u003c\/b\u003e\u003c\/li\u003e\n\u003cli aria-level=\"1\"\u003e\u003cb\u003eCognitive support and neuroprotection\u003c\/b\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eThis combination is widely researched for its potential \u003c\/span\u003e\u003cb\u003eanti-aging, muscle-building, and metabolic-enhancing effects\u003c\/b\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003cb\u003eRESEARCH\u003c\/b\u003e\u003c\/h3\u003e\n\u003ch4\u003e\u003cb\u003eHow CJC-1295 and Ipamorelin Work Together\u003c\/b\u003e\u003c\/h4\u003e\n\u003cp\u003e\u003cspan\u003eBoth peptides \u003c\/span\u003e\u003cb\u003eincrease growth hormone levels\u003c\/b\u003e\u003cspan\u003e, but they do so through \u003c\/span\u003e\u003cb\u003edifferent biological pathways\u003c\/b\u003e\u003cspan\u003e:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\"\u003e\n\u003cb\u003eCJC-1295\u003c\/b\u003e\u003cspan\u003e binds to \u003c\/span\u003e\u003cb\u003eGHRH receptors\u003c\/b\u003e\u003cspan\u003e, triggering \u003c\/span\u003e\u003cb\u003esustained GH release in a natural pulsatile cycle\u003c\/b\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli aria-level=\"1\"\u003e\n\u003cb\u003eIpamorelin\u003c\/b\u003e\u003cspan\u003e stimulates the \u003c\/span\u003e\u003cb\u003eGH secretagogue receptor (GHSR-1a)\u003c\/b\u003e\u003cspan\u003e, mimicking \u003c\/span\u003e\u003cb\u003eghrelin’s effects\u003c\/b\u003e\u003cspan\u003e while avoiding excessive \u003c\/span\u003e\u003cb\u003ecortisol and prolactin elevation\u003c\/b\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eBy \u003c\/span\u003e\u003cb\u003ecombining these mechanisms\u003c\/b\u003e\u003cspan\u003e, the peptides enhance \u003c\/span\u003e\u003cb\u003egrowth hormone signaling\u003c\/b\u003e\u003cspan\u003e while maintaining the body’s \u003c\/span\u003e\u003cb\u003enatural GH pulse rhythm\u003c\/b\u003e\u003cspan\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor research use only. Not for human consumption.\u003c\/em\u003e\u003c\/p\u003e","brand":"Peptides Verse","offers":[{"title":"Default Title","offer_id":51566090256617,"sku":null,"price":52.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/Tone_CJC-1295_Without_DAC_5mg_Ipamorelin_5mg_GH-Secretion_01_jpg.jpg?v=1784707599"},{"product_id":"cjc-1295-dac-5mg","title":"CJC-1295 DAC · Long-Acting GHRH Analogue · Albumin-Binding · GH-Release Research","description":"OVERVIEW\nCJC-1295 is a synthetic analogue of growth hormone-releasing hormone (GHRH) designed to increase plasma levels of growth hormone (GH) and insulin-like growth factor-1 (IGF-1). It is derived from the first 29 amino acids of GHRH, similar to Sermorelin and Modified GRF (1-29), but modified for enhanced stability and efficacy.\nThe DAC (Drug Affinity Complex) version of CJC-1295 includes an additional lysine linker, allowing it to bind to albumin, significantly extending its half-life. This prolonged activity leads to sustained GH release, reducing the need for frequent dosing compared to non-DAC versions.\nKey Benefits of CJC-1295 DAC:\n\nIncreases GH and IGF-1 levels\nEnhances protein synthesis and muscle recovery\nBoosts fat metabolism and supports weight management\nImproves sleep quality and cognitive function\nPreserves natural GH pulsatility, reducing side effects\n\nRESEARCH\nCJC-1295 and Growth Hormone Release\nCJC-1295 binds to GHRH receptors, triggering GH secretion while maintaining the body’s natural pulsatile rhythm. Research findings indicate that:\n\nA single dose of CJC-1295 can increase GH levels by 2-10 times.\nPeak GH secretion occurs around 2 hours post-administration and remains elevated for 6-8 days.\nUnlike exogenous GH injections, which can suppress natural GH production, CJC-1295 stimulates endogenous GH release, minimizing suppression risks.\n\nComparison: CJC-1295 vs. CJC-1295 DAC\n\n\n\nFeature\nCJC-1295 (No DAC)\nCJC-1295 DAC\n\n\nHalf-Life\n~30 minutes\n~8 days\n\n\nDosing Frequency\nMultiple injections daily\nWeekly\n\n\nMechanism\nShort-acting GHRH analogue\nBinds to albumin for sustained GH release\n\n\n\nThe DAC modification allows CJC-1295 to stay in circulation longer, preventing rapid degradation, and promoting longer-lasting GH stimulation.\nEffects on Muscle Growth\nAnimal studies suggest that CJC-1295 enhances lean body mass through:\n\nIncreased protein synthesis, supporting muscle hypertrophy and faster recovery.\nImproved nitrogen retention, aiding in muscle maintenance.\nEnhanced mitochondrial function, potentially boosting endurance and energy production.\n\nCJC-1295 and Fat Metabolism\nCJC-1295 has been linked to fat reduction and improved metabolic function by:\n\nEnhancing GH-induced fatty acid oxidation, leading to more efficient fat breakdown.\nReducing fat accumulation, particularly visceral and subcutaneous fat.\nImproving insulin sensitivity, which helps regulate glucose levels and metabolic efficiency.\n\nClinical studies indicate significant fat loss in subjects using CJC-1295 over 12-24 weeks.\nCJC-1295 and Sleep Quality\nResearch suggests that CJC-1295 may play a role in enhancing sleep cycles, particularly:\n\nIncreasing deep (slow-wave) sleep, crucial for muscle repair, memory consolidation, and recovery.\nModulating cortisol and stress hormones, leading to better relaxation and stress resilience.\n\nThese sleep-related benefits contribute to overall well-being, cognitive function, and physical recovery.\nCJC-1295 and Anti-Aging Potential\nDue to its ability to boost GH and IGF-1 levels, CJC-1295 has been explored for its potential in longevity and regenerative medicine. Benefits may include:\n\nImproved bone density, reducing age-related bone loss.\nEnhanced skin elasticity and collagen production, contributing to youthful skin.\nCognitive protection, potentially aiding in neuroprotection and memory retention.\n\nSTRUCTURE\n\nMolecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂\nMolecular Weight: 3647.954 g\/mol\nAmino Acid Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys-DAC\nCAS Registry Number: 446262-90-4\nPubChem Identifier: 91976842\n\nCITATIONS\n\nIonescu, M., \u0026amp; Frohman, L. A. Pulsatile secretion of growth hormone persists during continuous stimulation by CJC-1295. J. Clin. Endocrinol. Metab. (2006).\nAlba, M. et al. Once-daily administration of CJC-1295, a long-acting GHRH analog, normalizes growth in knockout mice. Am. J. Physiol. Endocrinol. Metab. (2006).\nVolpe, A. et al. Clinical use of growth hormone-releasing factor for induction of superovulation. Hum. Reprod. (1991).\nJetté, L. et al. hGRF1-29-Albumin Bioconjugates Activate the GRF Receptor on the Anterior Pituitary in Rats.Research Gate (2005).\nFor research use only. Not for human consumption.","brand":"Biogenesis Peptides","offers":[{"title":"Default Title","offer_id":51566091632873,"sku":"PS026","price":55.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/CJC-1295_DAC_Long-Acting_GHRH_Analogue_Albumin-Binding_01_jpg.jpg?v=1784707646"},{"product_id":"cjc-1295-without-dac-5mg","title":"CJC-1295 Without DAC · Short-Acting GHRH Analogue · Natural GH Pulse · GH-Release Research","description":"\u003cp\u003eOVERVIEW\u003cbr\u003e\nCJC-1295 Without DAC is a synthetic growth hormone-releasing hormone (GHRH) analog designed to increase endogenous growth hormone (GH) and insulin-like growth factor-1 (IGF-1) levels. Initially developed for medical applications, CJC-1295 has gained attention in research due to its ability to:\u003c\/p\u003e\n\n\u003cp\u003eStimulate GH secretion and prolong its half-life\u003cbr\u003e\nEnhance protein synthesis and muscle growth\u003cbr\u003e\nSupport fat metabolism and improve body composition\u003cbr\u003e\nPromote cellular repair and longevity\u003cbr\u003e\nImprove sleep quality and cognitive function\u003c\/p\u003e\n\n\u003cp\u003eUnlike CJC-1295 with DAC (Drug Affinity Complex), which provides sustained GH release, the version without DAC offers a more natural pulsatile release pattern, closely mimicking physiological GH secretion.\u003cbr\u003e\nRESEARCH\u003cbr\u003e\nCJC-1295 and Growth Hormone Secretion\u003cbr\u003e\nCJC-1295 Without DAC functions by binding to the growth hormone-releasing hormone receptor (GHRHR) in the pituitary gland, leading to an increase in GH release. Studies suggest that:\u003c\/p\u003e\n\n\u003cp\u003eGH pulsatility is essential for muscle growth, metabolic regulation, and overall physiological balance.\u003cbr\u003e\nCJC-1295 without DAC enhances GH release without significantly affecting prolactin levels.\u003cbr\u003e\nResearch indicates that combining CJC-1295 without DAC with a GH secretagogue like Ipamorelin may amplify its effects.\u003c\/p\u003e\n\n\u003cp\u003eCJC-1295 and Muscle Growth \u0026amp; Recovery\u003cbr\u003e\nAs an essential regulator of GH, CJC-1295 has been studied for its potential role in enhancing muscle repair, protein synthesis, and strength development. Key findings include:\u003c\/p\u003e\n\n\u003cp\u003eIncreased lean muscle mass and reduction in fat mass.\u003cbr\u003e\nFaster muscle recovery after intense exercise or injury.\u003cbr\u003e\nPotential benefits in age-related muscle wasting conditions.\u003c\/p\u003e\n\n\u003cp\u003eCJC-1295 and Fat Metabolism\u003cbr\u003e\nGrowth hormone is known to influence lipid metabolism, and research on CJC-1295 suggests:\u003c\/p\u003e\n\n\u003cp\u003eEnhanced lipolysis, leading to improved fat loss.\u003cbr\u003e\nRegulation of adipose tissue distribution, supporting a leaner physique.\u003cbr\u003e\nIncreased metabolic rate, contributing to better energy balance.\u003c\/p\u003e\n\n\u003cp\u003eCJC-1295 and Anti-Aging Research\u003cbr\u003e\nCJC-1295 Without DAC has been explored for its role in longevity and cellular repair. Research indicates:\u003c\/p\u003e\n\n\u003cp\u003eEnhanced collagen production, potentially improving skin elasticity and joint health.\u003cbr\u003e\nCellular regeneration and neuroprotection, which may benefit cognitive function.\u003cbr\u003e\nImproved sleep cycles due to its influence on deep sleep stages.\u003c\/p\u003e\n\n\u003cp\u003eSTRUCTURE\u003c\/p\u003e\n\n\u003cp\u003eMolecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂\u003cbr\u003e\nMolecular Weight: 3367.9 g\/mol\u003cbr\u003e\nCAS Registry Number: 863288-34-0\u003cbr\u003e\nPurity: 99% HPLC\u003c\/p\u003e\n\n\u003cp\u003eRESEARCH USE ONLY\u003cbr\u003e\nCJC-1295 Without DAC is strictly intended for research and laboratory purposes. It is not for human or veterinary use and is not intended for therapeutic or diagnostic applications.\u003c\/p\u003e\nFor research use only. Not for human consumption.","brand":"Biogenesis Peptides","offers":[{"title":"Default Title","offer_id":51566091665641,"sku":"PS025","price":40.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/CJC-1295_Without_DAC_Short-Acting_GHRH_Analogue_Natural_GH_01_jpg.jpg?v=1784707647"}],"url":"https:\/\/peptidesverse.com\/collections\/cjc-1295.oembed","provider":"Peptides Verse","version":"1.0","type":"link"}